TRIM22 activates NF-κB signaling in glioblastoma by accelerating the degradation of IκBα

NF-κB signaling plays a critical role in tumor growth and treatment resistance in GBM as in many other cancers. However, the molecular mechanisms underlying high, constitutive NF-κB activity in GBM remains to be elucidated. Here, we screened a panel of tripartite motif (TRIM) family proteins and ide...

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Detalles Bibliográficos
Autores principales: Ji, Jianxiong, Ding, Kaikai, Luo, Tao, Zhang, Xin, Chen, Anjing, Zhang, Di, Li, Gang, Thorsen, Frits, Huang, Bin, Li, Xingang, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7853150/
https://www.ncbi.nlm.nih.gov/pubmed/32814880
http://dx.doi.org/10.1038/s41418-020-00606-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7853150/
https://www.ncbi.nlm.nih.gov/pubmed/32814880
http://dx.doi.org/10.1038/s41418-020-00606-w

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