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BRPF3-HUWE1-mediated regulation of MYST2 is required for differentiation and cell-cycle progression in embryonic stem cells

Brpf-histone acetyltransferase (HAT) complexes have important roles in embryonic development and regulating differentiation in ESCs. Among Brpf family, Brpf3 is a scaffold protein of Myst2 histone acetyltransferase complex that plays crucial roles in gene regulation, DNA replication, development as...

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Detalles Bibliográficos
Autores principales: Cho, Hye In, Kim, Min Seong, Lee, Jina, Yoo, Byong Chul, Kim, Kyung Hee, Choe, Kwang-Min, Jang, Yeun Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7853152/
https://www.ncbi.nlm.nih.gov/pubmed/32555450
http://dx.doi.org/10.1038/s41418-020-0577-1