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Potential Transcriptional Biomarkers to Guide Glucocorticoid Replacement in Autoimmune Addison’s Disease

BACKGROUND: No reliable biomarkers exist to guide glucocorticoid (GC) replacement treatment in autoimmune Addison’s disease (AAD), leading to overtreatment with alarming and persistent side effects or undertreatment, which could be fatal. OBJECTIVE: To explore changes in gene expression following di...

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Detalles Bibliográficos
Autores principales: Sævik, Åse Bjorvatn, Wolff, Anette B, Björnsdottir, Sigridur, Simunkova, Katerina, Hynne, Martha Schei, Dolan, David William Peter, Bratland, Eirik, Knappskog, Per M, Methlie, Paal, Carlsen, Siri, Isaksson, Magnus, Bensing, Sophie, Kämpe, Olle, Husebye, Eystein S, Løvås, Kristian, Øksnes, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7853175/
https://www.ncbi.nlm.nih.gov/pubmed/33553982
http://dx.doi.org/10.1210/jendso/bvaa202