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The role of aquaporin-4 in optic nerve head astrocytes in experimental glaucoma

PURPOSE: To study aquaporin channel expression in astrocytes of the mouse optic nerve (ON) and the response to IOP elevation in mice lacking aquaporin 4 (AQP4 null). METHODS: C57BL/6 (B6) and AQP4 null mice were exposed to bead-induced IOP elevation for 3 days (3D-IOP), 1 and 6 weeks. Mouse ocular t...

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Detalles Bibliográficos
Autores principales: Kimball, Elizabeth, Schaub, Julie, Quillen, Sarah, Keuthan, Casey, Pease, Mary Ellen, Korneva, Arina, Quigley, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7853498/
https://www.ncbi.nlm.nih.gov/pubmed/33529207
http://dx.doi.org/10.1371/journal.pone.0244123