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RAFFI: Accurate and fast familial relationship inference in large scale biobank studies using RaPID
Inference of relationships from whole-genome genetic data of a cohort is a crucial prerequisite for genome-wide association studies. Typically, relationships are inferred by computing the kinship coefficients (ϕ) and the genome-wide probability of zero IBD sharing (π(0)) among all pairs of individua...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7853505/ https://www.ncbi.nlm.nih.gov/pubmed/33476339 http://dx.doi.org/10.1371/journal.pgen.1009315 |