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RAFFI: Accurate and fast familial relationship inference in large scale biobank studies using RaPID

Inference of relationships from whole-genome genetic data of a cohort is a crucial prerequisite for genome-wide association studies. Typically, relationships are inferred by computing the kinship coefficients (ϕ) and the genome-wide probability of zero IBD sharing (π(0)) among all pairs of individua...

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Detalles Bibliográficos
Autores principales: Naseri, Ardalan, Shi, Junjie, Lin, Xihong, Zhang, Shaojie, Zhi, Degui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7853505/
https://www.ncbi.nlm.nih.gov/pubmed/33476339
http://dx.doi.org/10.1371/journal.pgen.1009315

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