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Cross-effect of TRPV1 and EP3 receptor on coughs and bronchopulmonary C-neural activities

Prostaglandin E(2) (PGE(2))-induced coughs in vivo and vagal nerve depolarization in vitro are inhibited by systemic and local administration of prostaglandin EP3 receptor (L-798106) and TRPV1 antagonists (JNJ 17203212). These results indicate a modulating effect of TRPV1 on the EP3 receptor-mediate...

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Detalles Bibliográficos
Autores principales: Gao, Xiuping, Zhuang, Jianguo, Zhao, Lei, Wei, Wan, Xu, Fadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7853511/
https://www.ncbi.nlm.nih.gov/pubmed/33529249
http://dx.doi.org/10.1371/journal.pone.0246375