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Strand-Specific Reverse Transcription PCR for Detection of Replicating SARS-CoV-2

We developed an assay that detects minus-strand RNA as a surrogate for actively replicating severe acute respiratory syndrome coronavirus 2. We detected minus-strand RNA in 41 persons with coronavirus disease up to 30 days after symptom onset. This assay might inform clinical decision-making about p...

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Detalles Bibliográficos
Autores principales: Hogan, Catherine A., Huang, ChunHong, Sahoo, Malaya K., Wang, Hannah, Jiang, Becky, Sibai, Mamdouh, Holubar, Marisa, Mathew, Roshni, Zehnder, James, Pinsky, Benjamin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7853532/
https://www.ncbi.nlm.nih.gov/pubmed/33496233
http://dx.doi.org/10.3201/eid2702.204168