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Thymoproteasome-Expressing Mesenchymal Stromal Cells Confer Protective Anti-Tumor Immunity via Cross-Priming of Endogenous Dendritic Cells

Proteasomes are complex macromolecular structures existing in various forms to regulate a myriad of cellular processes. Besides degrading unwanted or misfolded proteins (proteostasis), distinct immune functions were ascribed for the immunoproteasome and thymoproteasome (TPr) complexes. For instance,...

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Detalles Bibliográficos
Autores principales: Bikorimana, Jean-Pierre, El-Hachem, Nehme, El-Kadiry, Abed El-Hakim, Abusarah, Jamilah, Salame, Natasha, Shammaa, Riam, Rafei, Moutih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7853649/
https://www.ncbi.nlm.nih.gov/pubmed/33542714
http://dx.doi.org/10.3389/fimmu.2020.596303