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Thymoproteasome-Expressing Mesenchymal Stromal Cells Confer Protective Anti-Tumor Immunity via Cross-Priming of Endogenous Dendritic Cells
Proteasomes are complex macromolecular structures existing in various forms to regulate a myriad of cellular processes. Besides degrading unwanted or misfolded proteins (proteostasis), distinct immune functions were ascribed for the immunoproteasome and thymoproteasome (TPr) complexes. For instance,...
Autores principales: | Bikorimana, Jean-Pierre, El-Hachem, Nehme, El-Kadiry, Abed El-Hakim, Abusarah, Jamilah, Salame, Natasha, Shammaa, Riam, Rafei, Moutih |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7853649/ https://www.ncbi.nlm.nih.gov/pubmed/33542714 http://dx.doi.org/10.3389/fimmu.2020.596303 |
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