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Clinical Applications of Single-Stranded Oligonucleotides: Current Landscape of Approved and In-Development Therapeutics

Single-stranded oligonucleotides have been explored as a therapeutic modality for more than 20 years. Only during the last 5 years have single-stranded oligonucleotides become a modality of choice in the fields of precision medicine and targeted therapeutics. Recently, there have been a number of de...

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Detalles Bibliográficos
Autores principales: Scharner, Juergen, Aznarez, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854307/
https://www.ncbi.nlm.nih.gov/pubmed/33359792
http://dx.doi.org/10.1016/j.ymthe.2020.12.022