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Anticonvulsant Effectiveness and Neurotoxicity Profile of 4-butyl-5-[(4-chloro-2-methylphenoxy)methyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione (TPL-16) in Mice

Protective (antiseizure) effects of 4-butyl-5-[(4-chloro-2-methylphenoxy)-methyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione (TPL-16) and acute neurotoxic effects were determined in the tonic-clonic seizure model and rotarod test in mice. The interaction profile of four classic antiepileptic drugs (carb...

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Detalles Bibliográficos
Autores principales: Drabik, Magdalena, Głuszak, Mariusz, Wróblewska-Łuczka, Paula, Plewa, Zbigniew, Jankiewicz, Marek, Kozińska, Justyna, Florek-Łuszczki, Magdalena, Plech, Tomasz, Łuszczki, Jarogniew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854423/
https://www.ncbi.nlm.nih.gov/pubmed/33206316
http://dx.doi.org/10.1007/s11064-020-03175-z