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Enhanced GABAergic Inhibition of Cholinergic Interneurons in the zQ175(+/−) Mouse Model of Huntington's Disease
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder that initially manifests itself in the striatum. How intrastriatal circuitry is altered by the disease is poorly understood. To help fill this gap, the circuitry linking spiny projection neurons (SPNs) to cholinergic...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854471/ https://www.ncbi.nlm.nih.gov/pubmed/33551760 http://dx.doi.org/10.3389/fnsys.2020.626412 |