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Photoactivatable CaMKII induces synaptic plasticity in single synapses

Optogenetic approaches for studying neuronal functions have proven their utility in the neurosciences. However, optogenetic tools capable of inducing synaptic plasticity at the level of single synapses have been lacking. Here, we engineered a photoactivatable (pa)CaMKII by fusing a light-sensitive d...

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Detalles Bibliográficos
Autores principales: Shibata, Akihiro C. E., Ueda, Hiromi H., Eto, Kei, Onda, Maki, Sato, Aiko, Ohba, Tatsuko, Nabekura, Junichi, Murakoshi, Hideji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854602/
https://www.ncbi.nlm.nih.gov/pubmed/33531495
http://dx.doi.org/10.1038/s41467-021-21025-6