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Association of PET-based estradiol-challenge test for breast cancer progesterone receptors with response to endocrine therapy

Estrogen receptor (ER) testing of breast cancer imperfectly predicts response to endocrine therapy (ET). We hypothesize that a brief estradiol challenge will increase tumor progesterone receptor (PgR) levels only in tumors with functional ER. In this prospective, phase 2, single-center, single-arm t...

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Detalles Bibliográficos
Autores principales: Dehdashti, Farrokh, Wu, Ningying, Ma, Cynthia X., Naughton, Michael J., Katzenellenbogen, John A., Siegel, Barry A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854611/
https://www.ncbi.nlm.nih.gov/pubmed/33531464
http://dx.doi.org/10.1038/s41467-020-20814-9