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Host immunity modulates the efficacy of microbiota transplantation for treatment of Clostridioides difficile infection

Fecal microbiota transplantation (FMT) is a successful therapeutic strategy for treating recurrent Clostridioides difficile infection. Despite remarkable efficacy, implementation of FMT therapy is limited and the mechanism of action remains poorly understood. Here, we demonstrate a critical role for...

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Detalles Bibliográficos
Autores principales: Littmann, Eric R., Lee, Jung-Jin, Denny, Joshua E., Alam, Zahidul, Maslanka, Jeffrey R., Zarin, Isma, Matsuda, Rina, Carter, Rebecca A., Susac, Bože, Saffern, Miriam S., Fett, Bryton, Mattei, Lisa M., Bittinger, Kyle, Abt, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854624/
https://www.ncbi.nlm.nih.gov/pubmed/33531483
http://dx.doi.org/10.1038/s41467-020-20793-x