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Association between methylation of BIN1 promoter in peripheral blood and preclinical Alzheimer’s disease

The bridging integrator 1 (BIN1) gene is the second most important susceptibility gene for late-onset Alzheimer’s disease (LOAD) after apolipoprotein E (APOE) gene. To explore whether the BIN1 methylation in peripheral blood changed in the early stage of LOAD, we included 814 participants (484 cogni...

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Detalles Bibliográficos
Autores principales: Hu, Hao, Tan, Lan, Bi, Yan-Lin, Xu, Wei, Tan, Lin, Shen, Xue-Ning, Hou, Xiao-He, Ma, Ya-Hui, Dong, Qiang, Yu, Jin-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854626/
https://www.ncbi.nlm.nih.gov/pubmed/33531457
http://dx.doi.org/10.1038/s41398-021-01218-9