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TGFβ signalling acts as a molecular brake of myoblast fusion

Fusion of nascent myoblasts to pre-existing myofibres is critical for skeletal muscle growth and repair. The vast majority of molecules known to regulate myoblast fusion are necessary in this process. Here, we uncover, through high-throughput in vitro assays and in vivo studies in the chicken embryo...

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Detalles Bibliográficos
Autores principales: Melendez, Julie, Sieiro, Daniel, Salgado, David, Morin, Valérie, Dejardin, Marie-Julie, Zhou, Chan, Mullen, Alan C., Marcelle, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854724/
https://www.ncbi.nlm.nih.gov/pubmed/33531476
http://dx.doi.org/10.1038/s41467-020-20290-1