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TGFβ signalling acts as a molecular brake of myoblast fusion
Fusion of nascent myoblasts to pre-existing myofibres is critical for skeletal muscle growth and repair. The vast majority of molecules known to regulate myoblast fusion are necessary in this process. Here, we uncover, through high-throughput in vitro assays and in vivo studies in the chicken embryo...
Autores principales: | Melendez, Julie, Sieiro, Daniel, Salgado, David, Morin, Valérie, Dejardin, Marie-Julie, Zhou, Chan, Mullen, Alan C., Marcelle, Christophe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854724/ https://www.ncbi.nlm.nih.gov/pubmed/33531476 http://dx.doi.org/10.1038/s41467-020-20290-1 |
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