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DeePaN: deep patient graph convolutional network integrating clinico-genomic evidence to stratify lung cancers for immunotherapy

Immuno-oncology (IO) therapies have transformed the therapeutic landscape of non-small cell lung cancer (NSCLC). However, patient responses to IO are variable and influenced by a heterogeneous combination of health, immune, and tumor factors. There is a pressing need to discover the distinct NSCLC s...

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Detalles Bibliográficos
Autores principales: Fang, Chao, Xu, Dong, Su, Jing, Dry, Jonathan R, Linghu, Bolan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854753/
https://www.ncbi.nlm.nih.gov/pubmed/33531613
http://dx.doi.org/10.1038/s41746-021-00381-z