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TGFβ signaling curbs cell fusion and muscle regeneration

Muscle cell fusion is a multistep process involving cell migration, adhesion, membrane remodeling and actin-nucleation pathways to generate multinucleated myotubes. However, molecular brakes restraining cell–cell fusion events have remained elusive. Here we show that transforming growth factor beta...

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Detalles Bibliográficos
Autores principales: Girardi, Francesco, Taleb, Anissa, Ebrahimi, Majid, Datye, Asiman, Gamage, Dilani G., Peccate, Cécile, Giordani, Lorenzo, Millay, Douglas P., Gilbert, Penney M., Cadot, Bruno, Le Grand, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854756/
https://www.ncbi.nlm.nih.gov/pubmed/33531466
http://dx.doi.org/10.1038/s41467-020-20289-8