Cargando…
TGFβ signaling curbs cell fusion and muscle regeneration
Muscle cell fusion is a multistep process involving cell migration, adhesion, membrane remodeling and actin-nucleation pathways to generate multinucleated myotubes. However, molecular brakes restraining cell–cell fusion events have remained elusive. Here we show that transforming growth factor beta...
Autores principales: | Girardi, Francesco, Taleb, Anissa, Ebrahimi, Majid, Datye, Asiman, Gamage, Dilani G., Peccate, Cécile, Giordani, Lorenzo, Millay, Douglas P., Gilbert, Penney M., Cadot, Bruno, Le Grand, Fabien |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854756/ https://www.ncbi.nlm.nih.gov/pubmed/33531466 http://dx.doi.org/10.1038/s41467-020-20289-8 |
Ejemplares similares
-
Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development
por: Quinn, Malgorzata E., et al.
Publicado: (2017) -
Myomerger promotes fusion pore by elastic coupling between proximal membrane leaflets and hemifusion diaphragm
por: Golani, Gonen, et al.
Publicado: (2021) -
Reply to: holistic effort at curbing tobacco use essential in the US
por: Ebrahimi Kalan, Mohammad, et al.
Publicado: (2023) -
Phosphatidylserine orchestrates Myomerger membrane insertions to drive myoblast fusion
por: Gamage, Dilani G., et al.
Publicado: (2022) -
Curbing Inflammation
por: Landis, R. Clive, et al.
Publicado: (2013)