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Monocytes complexed to platelets differentiate into functionally deficient dendritic cells

In addition to their role in hemostasis, platelets store numerous immunoregulatory molecules such as CD40L, TGFβ, β2‐microglobulin, and IL‐1β and release them upon activation. Previous studies indicate that activated platelets form transient complexes with monocytes, especially in HIV infected indiv...

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Detalles Bibliográficos
Autores principales: Singh, Meera V., Suwunnakorn, Sumanun, Simpson, Sydney R., Weber, Emily A., Singh, Vir B., Kalinski, Pawel, Maggirwar, Sanjay B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854860/
https://www.ncbi.nlm.nih.gov/pubmed/32663904
http://dx.doi.org/10.1002/JLB.3A0620-460RR