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Leptin signaling in vagal afferent neurons supports the absorption and storage of nutrients from high-fat diet

OBJECTIVE: Activation of vagal afferent neurons (VAN) by postprandial gastrointestinal signals terminates feeding and facilitates nutrient digestion and absorption. Leptin modulates responsiveness of VAN to meal-related gastrointestinal signals. Rodents with high-fat diet (HF) feeding develop leptin...

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Detalles Bibliográficos
Autores principales: Huang, Kuei-Pin, Goodson, Michael L, Vang, Wendie, Li, Hui, Page, Amanda J, Raybould, Helen E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854885/
https://www.ncbi.nlm.nih.gov/pubmed/32917985
http://dx.doi.org/10.1038/s41366-020-00678-1