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Optogenetic manipulation of an ascending arousal system tunes cortical broadband gamma power and reveals functional deficits relevant to schizophrenia

Increases in broadband cortical electroencephalogram (EEG) power in the gamma band (30–80 Hz) range have been observed in schizophrenia patients and in mouse models of schizophrenia. They are also seen in humans and animals treated with the psychotomimetic agent ketamine. However, the mechanisms whi...

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Detalles Bibliográficos
Autores principales: McNally, James M., Aguilar, David D., Katsuki, Fumi, Radzik, Leana, Schiffino, Felipe L., Uygun, David S., McKenna, James T., Strecker, Robert E., Deisseroth, Karl, Spencer, Kevin M., Brown, Ritchie E., Nat, Rer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855059/
https://www.ncbi.nlm.nih.gov/pubmed/32690865
http://dx.doi.org/10.1038/s41380-020-0840-3