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Contribution of Val/Ile87 residue in the extracellular domain in agonist-induced current responses of the human and rat P2X7 receptors

The P2X7 receptor (P2X7R) is an ATP-gated cation channel with a critical role in many physiological and pathological processes, and shows prominent functional differences across mammalian species, exemplified by larger current responses of the rat (r) P2X7R to ATP and its analogue BzATP and a greate...

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Detalles Bibliográficos
Autores principales: Caseley, Emily A, Muench, Stephen P, Jiang, Lin-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855165/
https://www.ncbi.nlm.nih.gov/pubmed/33029714
http://dx.doi.org/10.1007/s11302-020-09730-1