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Contribution of Val/Ile87 residue in the extracellular domain in agonist-induced current responses of the human and rat P2X7 receptors
The P2X7 receptor (P2X7R) is an ATP-gated cation channel with a critical role in many physiological and pathological processes, and shows prominent functional differences across mammalian species, exemplified by larger current responses of the rat (r) P2X7R to ATP and its analogue BzATP and a greate...
Autores principales: | Caseley, Emily A, Muench, Stephen P, Jiang, Lin-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855165/ https://www.ncbi.nlm.nih.gov/pubmed/33029714 http://dx.doi.org/10.1007/s11302-020-09730-1 |
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