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The Small Molecule BIBR1532 Exerts Potential Anti-cancer Activities in Preclinical Models of Feline Oral Squamous Cell Carcinoma Through Inhibition of Telomerase Activity and Down-Regulation of TERT

Expression of telomerase reverse transcriptase (TERT) and telomerase activity (TA) is a main feature of cancer, contributing to cell immortalization by causing telomeres dysfunction. BIBR1532 is a potent telomerase inhibitor that showed potential anti-tumor activities in several types of cancer, by...

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Detalles Bibliográficos
Autores principales:	Altamura, Gennaro, degli Uberti, Barbara, Galiero, Giorgio, De Luca, Giovanna, Power, Karen, Licenziato, Luca, Maiolino, Paola, Borzacchiello, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Veterinary Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855307/ https://www.ncbi.nlm.nih.gov/pubmed/33553285 http://dx.doi.org/10.3389/fvets.2020.620776

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