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Discrete-state stochastic kinetic models for target DNA search by proteins: Theory and experimental applications

To perform their functions, transcription factors and DNA-repair/modifying enzymes randomly search DNA in order to locate their specific targets on DNA. Discrete-state stochastic kinetic models have been developed to explain how the efficiency of the search process is influenced by the molecular pro...

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Detalles Bibliográficos
Autores principales: Iwahara, Junji, Kolomeisky, Anatoly B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855466/
https://www.ncbi.nlm.nih.gov/pubmed/33338872
http://dx.doi.org/10.1016/j.bpc.2020.106521