TET2 chemically modifies tRNAs and regulates tRNA fragment levels

The Ten-eleven Translocation 2 (TET2) protein, which oxidizes 5-methylcytosine in DNA, can also bind RNA; however, the targets and function of TET2–RNA interactions in vivo are not fully understood. Using stringent affinity tags introduced at the Tet2 locus, we purified and sequenced TET2-crosslinke...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Chongsheng, Bozler, Julianna, Janssen, Kevin A., Wilusz, Jeremy E., Garcia, Benjamin A., Schorn, Andrea J., Bonasio, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855721/
https://www.ncbi.nlm.nih.gov/pubmed/33230319
http://dx.doi.org/10.1038/s41594-020-00526-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855721/
https://www.ncbi.nlm.nih.gov/pubmed/33230319
http://dx.doi.org/10.1038/s41594-020-00526-w

Ejemplares similares