Cargando…
TET2 chemically modifies tRNAs and regulates tRNA fragment levels
The Ten-eleven Translocation 2 (TET2) protein, which oxidizes 5-methylcytosine in DNA, can also bind RNA; however, the targets and function of TET2–RNA interactions in vivo are not fully understood. Using stringent affinity tags introduced at the Tet2 locus, we purified and sequenced TET2-crosslinke...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855721/ https://www.ncbi.nlm.nih.gov/pubmed/33230319 http://dx.doi.org/10.1038/s41594-020-00526-w |