CSF1R Inhibition Depletes Tumor-Associated Macrophages and Attenuates Tumor Progression in a Mouse Sonic Hedgehog-Medulloblastoma Model

The immune microenvironment of tumors can play a critical role in promoting or inhibiting tumor progression depending on the context. We present evidence that tumor-associated macrophages/microglia (TAMs) can promote tumor progression in the sonic hedgehog subgroup of medulloblastoma (SHH-MB). By co...

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Detalles Bibliográficos
Autores principales: Tan, I-Li, Arifa, Raquel Duque Nascimento, Rallapalli, Harikrishna, Kana, Veronika, Lao, Zhimin, Sanghrajka, Reeti Mayur, Bayin, N. Sumru, Tanne, Antoine, Wojcinski, Alexandre, Korshunov, Andrey, Bhardwaj, Nina, Merad, Miriam, Turnbull, Daniel H., Lafaille, Juan J., Joyner, Alexandra L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855734/
https://www.ncbi.nlm.nih.gov/pubmed/33159168
http://dx.doi.org/10.1038/s41388-020-01536-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855734/
https://www.ncbi.nlm.nih.gov/pubmed/33159168
http://dx.doi.org/10.1038/s41388-020-01536-0

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