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HDAC6 promotes growth, migration/invasion and self-renewal of rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is a devastating pediatric sarcoma. The survival outcomes remain poor for patients with relapsed or metastatic disease. Effective targeted therapy is lacking due to our limited knowledge of the underlying cellular and molecular mechanisms leading to disease progression. In thi...

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Detalles Bibliográficos
Autores principales: Pham, Thao Q., Robinson, Kristin, Xu, Lin, Pavlova, Maria N., Skapek, Stephen X., Chen, Eleanor Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855743/
https://www.ncbi.nlm.nih.gov/pubmed/33199827
http://dx.doi.org/10.1038/s41388-020-01550-2