Structural and functional characterization of the Spo11 core complex

Spo11, which makes DNA double-strand breaks (DSBs) essential for meiotic recombination, has long been recalcitrant to biochemical study. We provide molecular analysis of S. cerevisiae Spo11 purified with partners Rec102, Rec104 and Ski8. Rec102 and Rec104 jointly resemble the B subunit of archaeal T...

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Detalles Bibliográficos
Autores principales: Claeys Bouuaert, Corentin, Tischfield, Sam E., Pu, Stephen, Mimitou, Eleni P., Arias-Palomo, Ernesto, Berger, James M., Keeney, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855791/
https://www.ncbi.nlm.nih.gov/pubmed/33398171
http://dx.doi.org/10.1038/s41594-020-00534-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855791/
https://www.ncbi.nlm.nih.gov/pubmed/33398171
http://dx.doi.org/10.1038/s41594-020-00534-w

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