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Structural and functional characterization of the Spo11 core complex
Spo11, which makes DNA double-strand breaks (DSBs) essential for meiotic recombination, has long been recalcitrant to biochemical study. We provide molecular analysis of S. cerevisiae Spo11 purified with partners Rec102, Rec104 and Ski8. Rec102 and Rec104 jointly resemble the B subunit of archaeal T...
Autores principales: | Claeys Bouuaert, Corentin, Tischfield, Sam E., Pu, Stephen, Mimitou, Eleni P., Arias-Palomo, Ernesto, Berger, James M., Keeney, Scott |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855791/ https://www.ncbi.nlm.nih.gov/pubmed/33398171 http://dx.doi.org/10.1038/s41594-020-00534-w |
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