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BRD4 regulates key transcription factors that drive epithelial-mesenchymal transition in castration-resistant prostate cancer

BACKGROUND: Androgen deprivation therapies for the hormone-dependent stages of prostate cancer have become so effective that new forms of chemoresistant tumors are emerging in clinical practice, and require new targeted therapies in the metastatic setting. Yet there are important gaps in our underst...

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Detalles Bibliográficos
Autores principales: Shafran, Jordan S., Jafari, Naser, Casey, Allison N., Győrffy, Balázs, Denis, Gerald V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855805/
https://www.ncbi.nlm.nih.gov/pubmed/32690869
http://dx.doi.org/10.1038/s41391-020-0246-y