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Intranasal Administration of PACAP Is an Efficient Delivery Route to Reduce Infarct Volume and Promote Functional Recovery After Transient and Permanent Middle Cerebral Artery Occlusion

Intranasal (IN) administration appears to be a suitable route for clinical use as it allows direct delivery of bioactive molecules to the central nervous system, reducing systemic exposure and sides effects. Nevertheless, only some molecules can be transported to the brain from the nasal cavity. Thi...

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Detalles Bibliográficos
Autores principales: Cherait, Asma, Maucotel, Julie, Lefranc, Benjamin, Leprince, Jérôme, Vaudry, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855853/
https://www.ncbi.nlm.nih.gov/pubmed/33551991
http://dx.doi.org/10.3389/fendo.2020.585082