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A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow‐Fed Young Adult Mice
Oxidized phospholipids containing phosphocholine (OxPL) are pro‐inflammatory lipid peroxidation products that bind to scavenger receptors (SRs), such as Scarb1, and toll‐like receptors (TLRs). Excessive OxPL, as found in oxidized low‐density lipoprotein (OxLDL), overwhelm these defense mechanisms an...
Autores principales: | Palmieri, Michela, Kim, Ha‐Neui, Gomez‐Acevedo, Horacio, Que, Xuchu, Tsimikas, Sotirios, Jilka, Robert L, Manolagas, Stavros C, Witztum, Joseph L, Ambrogini, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855899/ https://www.ncbi.nlm.nih.gov/pubmed/32990984 http://dx.doi.org/10.1002/jbmr.4173 |
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