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Simplified geometric representations of protein structures identify complementary interaction interfaces

Protein‐protein interactions are critical to protein function, but three‐dimensional (3D) arrangements of interacting proteins have proven hard to predict, even given the identities and 3D structures of the interacting partners. Specifically, identifying the relevant pairwise interaction surfaces re...

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Detalles Bibliográficos
Autores principales: McCafferty, Caitlyn L., Marcotte, Edward M., Taylor, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855953/
https://www.ncbi.nlm.nih.gov/pubmed/33140424
http://dx.doi.org/10.1002/prot.26020