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Targeted Chinese Medicine Delivery by A New Family of Biodegradable Pseudo-Protein Nanoparticles for Treating Triple-Negative Breast Cancer: In Vitro and In Vivo Study

Triple negative breast cancer (TNBC) has the worst overall survival among all breast cancer subtypes; 80% of TNBC harbors TP53 mutation. Gambogic acid (GA) is an herbal compound isolated from the dry brownish gamboge resin of Garcinia hanburyi. A new family of biodegradable polymer, the folate (FA)-...

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Detalles Bibliográficos
Autores principales: Kwan, Hiu Yee, Xu, Qinghua, Gong, Ruihong, Bian, Zhaoxiang, Chu, Chih-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855979/
https://www.ncbi.nlm.nih.gov/pubmed/33552972
http://dx.doi.org/10.3389/fonc.2020.600298