Nuclear partitioning of Prohibitin 1 inhibits Wnt/β-catenin-dependent intestinal tumorigenesis

The Wnt/β-catenin signaling pathway is aberrantly activated in the majority of colorectal cancer cases due to somatic mutations in the adenomatous polyposis coli (APC) gene. Prohibitin 1 (PHB1) serves pleiotropic cellular functions with dynamic subcellular trafficking facilitating signaling crosstal...

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Detalles Bibliográficos
Autores principales: Alula, Kibrom M., Delgado-Deida, Yaritza, Jackson, Dakota N., Venuprasad, K., Theiss, Arianne L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856018/
https://www.ncbi.nlm.nih.gov/pubmed/33144683
http://dx.doi.org/10.1038/s41388-020-01538-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856018/
https://www.ncbi.nlm.nih.gov/pubmed/33144683
http://dx.doi.org/10.1038/s41388-020-01538-y

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