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Functional characterization of uveal melanoma oncogenes
Uveal melanoma (UM) is a currently untreatable form of melanoma with a 50% mortality rate. Characterization of the essential signaling pathways driving this cancer is critical to develop target therapies. Activating mutations in the Gαq signaling pathway at the level of GNAQ, GNA11 or rarely CYSLTR2...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856047/ https://www.ncbi.nlm.nih.gov/pubmed/33262460 http://dx.doi.org/10.1038/s41388-020-01569-5 |