Brain pathology caused in the neonatal macaque by short and prolonged exposures to anticonvulsant drugs

Barbiturates and benzodiazepines are potent GABA(A) receptor agonists and strong anticonvulsants. In the developing brain they can cause neuronal and oligodendroglia apoptosis, impair synaptogenesis, inhibit neurogenesis and trigger long-term neurocognitive sequelae. In humans, the vulnerable period...

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Detalles Bibliográficos
Autores principales: Noguchi, Kevin K., Fuhler, Nicole A., Wang, Sophie H., Capuano, Saverio, Brunner, Kevin R., Larson, Shreya, Crosno, Kristin, Simmons, Heather A., Mejia, Andres F., Martin, Lauren D., Dissen, Gregory A., Brambrink, Ansgar, Ikonomidou, Chrysanthy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856070/
https://www.ncbi.nlm.nih.gov/pubmed/33385515
http://dx.doi.org/10.1016/j.nbd.2020.105245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856070/
https://www.ncbi.nlm.nih.gov/pubmed/33385515
http://dx.doi.org/10.1016/j.nbd.2020.105245

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