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Tetracyclines promote survival and fitness in mitochondrial disease models

Mitochondrial diseases (MD) are a heterogeneous group of disorders resulting from genetic mutations in nuclear or mitochondrial DNA (mtDNA) genes encoding for mitochondrial proteins (1,2). MD cause pathologies with severe tissue damage and ultimately death (3,4). There are no cures for MD and curren...

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Detalles Bibliográficos
Autores principales: Perry, Elizabeth A., Bennett, Christopher F., Luo, Chi, Balsa, Eduardo, Jedrychowski, Mark, O’Malley, Katherine, Latorre-Muro, Pedro, Ladley, Richard Porter, Reda, Kamar, Wright, Peter M., Gygi, Steve P., Myers, Andrew G., Puigserver, Pere
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856165/
https://www.ncbi.nlm.nih.gov/pubmed/33462515
http://dx.doi.org/10.1038/s42255-020-00334-y