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Alendronate and omeprazole in combination reduce angiogenic and growth signals from osteoblasts

OBJECTIVE: Due to gastrointestinal side effects of oral bisphosphonates (BPs), proton pump inhibitors (PPIs) are often prescribed. PPIs may enhance the risk of osteonecrosis of the jaw, a rare side effect of BPs. Therefore, the objective of this study was to evaluate the effects of the oral BP alend...

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Detalles Bibliográficos
Autores principales: Krüger, Tormod B., Herlofson, Bente B., Lian, Aina M., Syversen, Unni, Reseland, Janne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856318/
https://www.ncbi.nlm.nih.gov/pubmed/33553512
http://dx.doi.org/10.1016/j.bonr.2021.100750