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Structure-based peptide design targeting intrinsically disordered proteins: Novel histone H4 and H2A peptidic inhibitors

A growing body of research has demonstrated that targeting intrinsically disordered proteins (IDPs) and intrinsically disordered protein regions (IDPRs) is feasible and represents a new trending strategy in drug discovery. However, the number of inhibitors targeting IDPs/IDPRs is increasing slowly d...

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Detalles Bibliográficos
Autores principales: Wichapong, Kanin, Silvestre-Roig, Carlos, Braster, Quinte, Schumski, Ariane, Soehnlein, Oliver, Nicolaes, Gerry A.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856395/
https://www.ncbi.nlm.nih.gov/pubmed/33598107
http://dx.doi.org/10.1016/j.csbj.2021.01.026