Cargando…
Structure-based peptide design targeting intrinsically disordered proteins: Novel histone H4 and H2A peptidic inhibitors
A growing body of research has demonstrated that targeting intrinsically disordered proteins (IDPs) and intrinsically disordered protein regions (IDPRs) is feasible and represents a new trending strategy in drug discovery. However, the number of inhibitors targeting IDPs/IDPRs is increasing slowly d...
Autores principales: | Wichapong, Kanin, Silvestre-Roig, Carlos, Braster, Quinte, Schumski, Ariane, Soehnlein, Oliver, Nicolaes, Gerry A.F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856395/ https://www.ncbi.nlm.nih.gov/pubmed/33598107 http://dx.doi.org/10.1016/j.csbj.2021.01.026 |
Ejemplares similares
-
The role of extracellular histones in COVID‐19
por: de Vries, Femke, et al.
Publicado: (2022) -
Histone H3 Cleavage in Severe COVID-19 ICU Patients
por: Huckriede, Joram, et al.
Publicado: (2021) -
Inhibition of NET Release Fails to Reduce Adipose Tissue Inflammation in Mice
por: Braster, Quinte, et al.
Publicado: (2016) -
Conformational plasticity of ADAMTS13 in hemostasis and autoimmunity
por: Ercig, Bogac, et al.
Publicado: (2021) -
Atherosclerotic Plaque Destabilization in Mice: A Comparative Study
por: Hartwig, Helene, et al.
Publicado: (2015)