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Enhancing Catecholase Activity of a Recombinant Human Tyrosinase Through Multiple Strategies

BACKGROUND: Tyrosinases are copper-containing enzymes that initiate the melanin synthesis. They catalyze the direct oxidation of L-tyrosine or L-DOPA into L-DOPAquinone. OBJECTIVES: In present study, we aimed to obtain a recombinant tyrosinase with enhanced catecholase activity through site-directed...

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Detalles Bibliográficos
Autores principales: Shahrisa, Arman, Nikkhah, Maryam, Shirzad, Hadi, Behzadi, Roudabeh, Sadeghizadeh, Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Genetic Engineering and Biotechnology 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856396/
https://www.ncbi.nlm.nih.gov/pubmed/33542935
http://dx.doi.org/10.30498/IJB.2020.137293.2310