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Edoxaban, a direct oral factor Xa inhibitor, ameliorates coagulation, microvascular thrombus formation, and acute liver injury in a lipopolysaccharide-induced coagulopathy model in rats

Infection increases the risk of thrombosis through the activation of inflammation and coagulation. Edoxaban, a direct oral factor Xa inhibitor, is used for the prevention and treatment of thrombotic diseases. The aim of this study was to determine the effects of edoxaban on microvascular thrombus fo...

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Detalles Bibliográficos
Autores principales: Morishima, Yoshiyuki, Shibutani, Tomoko, Noguchi, Kengo, Ito, Yusuke, Honda, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856452/
https://www.ncbi.nlm.nih.gov/pubmed/33534029
http://dx.doi.org/10.1007/s11239-021-02381-y