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Diffusion and Protein Corona Formation of Lipid-Based Nanoparticles in the Vitreous Humor: Profiling and Pharmacokinetic Considerations

[Image: see text] The vitreous humor is the first barrier encountered by intravitreally injected nanoparticles. Lipid-based nanoparticles in the vitreous are studied by evaluating their diffusion with single-particle tracking technology and by characterizing their protein coronae with surface plasmo...

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Detalles Bibliográficos
Autores principales: Tavakoli, Shirin, Kari, Otto Kalevi, Turunen, Tiina, Lajunen, Tatu, Schmitt, Mechthild, Lehtinen, Julia, Tasaka, Fumitaka, Parkkila, Petteri, Ndika, Joseph, Viitala, Tapani, Alenius, Harri, Urtti, Arto, Subrizi, Astrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856631/
https://www.ncbi.nlm.nih.gov/pubmed/32584047
http://dx.doi.org/10.1021/acs.molpharmaceut.0c00411